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7,259,236 Title:

RBP1L1, a novel retinoblastoma binding protein-related gene encoding an antigenic epitope and methods of using thereof

Abstract:

Disclosed herein is a novel retinoblastoma binding protein-related gene that encodes an antigenic epitope, IKPSLGSKK (SEQ ID NO:3), which is differentially expressed in cancers, such as breast, lung, colon, pancreas, and ovarian cancer. Polynucleotides that encode and polypeptides that comprise the antigenic epitope and variants thereof are disclosed. Also, disclosed are methods of using the polynucleotides and polypeptides of the present invention in immunotherapies and immunoassays.

Claims:

I claim:

1. A purified polypeptide consisting of SEQ ID NO:3.

2. A purified polypeptide consisting of SEQ ID NO:25.

3. A composition comprising the polypeptide of claim 1.

4. A composition comprising the polypeptide of claim 2.